Prevalence of hepatic steatosis in women with polycystic ovary syndrome
January 2013
in “Journal of Human Reproductive Sciences”
TLDR Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
The study investigated the prevalence of nonalcoholic fatty liver disease (NAFLD) in 54 women with polycystic ovary syndrome (PCOS) compared to 55 healthy controls, finding a significantly higher occurrence of hepatic steatosis in the PCOS group (67% vs. 25%, P = 0.001). Additionally, women with PCOS had more cases of metabolic syndrome (35% vs. 7%, P < 0.01) and elevated transaminases (31% vs. 7%, P = 0.03). Factors linked to hepatic steatosis included age, body mass index (BMI), waist-hip ratio, insulin resistance, HDL levels, and a PCOS diagnosis. The study concluded that NAFLD is common in women with PCOS, particularly those with metabolic issues, and that liver disease evaluation should be considered earlier in these patients, especially if they show signs of metabolic syndrome.
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Cited in this study
research Increased androgen bioavailability is associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome
Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
research Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
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research Nonalcoholic fatty liver disease and polycystic ovary syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Prevalence of hepatic steatosis in women with polycystic ovary syndrome
Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.