New investigational drugs for androgenetic alopecia
April 2013
in “Expert Opinion on Investigational Drugs”
TLDR Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
This document from 10 years ago discusses various investigational drugs and therapies for androgenetic alopecia (AGA), the most common form of hair loss. The potential treatments include topical or intradermal delivery of 5-alfa-reductase inhibitors, prostaglandin analogs and antagonists, medications that act through the Wnt signaling pathway, stem cells for hair regeneration, platelet-rich plasma, and more effective ways of transplanting hair. The studies suggest that some of these treatments may be effective in promoting hair growth and increasing hair density, but more research is needed to confirm their efficacy. The document also highlights the complexity of hair follicle biology and the incomplete understanding of AGA.
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Cited in this study
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research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth
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research A randomized, single-blind trial of 5% minoxidil foam once daily versus 2% minoxidil solution twice daily in the treatment of androgenetic alopecia in women
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research Comparing the therapeutic effects of finasteride gel and tablet in treatment of the androgenetic alopecia
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research Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss
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