Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth
May 2016
in “Clinical, cosmetic and investigational dermatology”
TLDR FGF-2&D/P nanoparticles can help treat hair loss.
The study investigated the effects of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles (FGF-2&D/P NPs) on hair growth in 12 volunteers with thin hair. Participants applied 1 mL of FGF-2 (100 ng/mL) and D/P NPs (56 μg/mL) to their scalps twice daily for 6 months. Results showed a significant increase in hair diameter, with objective improvements in two cases and enhanced hair bounce and resilience in nine participants. The study concluded that transdermal application of FGF-2&D/P NPs could be a new treatment for alopecia.
View this study on dovepress.com →
Cited in this study
research Fibroblast Growth Factors Stimulate Hair Growth throughβ-Catenin and Shh Expression in C57BL/6 Mice
Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
research Potential targets in the discovery of new hair growth promoters for androgenic alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth
Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.
research Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles
Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
research Targeting to the hair follicles: Current status and potential
Hair follicles are promising targets for delivering drugs effectively.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Fibroblast growth factor and epidermal growth factor in hair development
FGF and EGF are crucial for hair follicle development and growth.
Related
research Hair loss (alopecia or baldness)
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
research Treatments of hereditary hair loss (alopecia)
Some treatments like minoxidil, finasteride, and surgery can help with hereditary hair loss.
research GainmoreTM M: An oral supplementation in men with Androgenic Alopecia for reduction in hair loss & new hair growth
Using body measurements can help achieve good results in plastic surgery like reshaping the torso, but it doesn't work for all body types.
research Hair Disorders Associated with Anticancer Agents
Some cancer treatments cause different types of hair loss, but scalp cooling can help prevent it.
research [Effectiveness of the treatment plan for androgenetic alopecia].
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.