Autologous Stem Cell-Derived Therapies for Androgenetic Alopecia: A Systematic Review of Randomized Control Trials on Efficacy, Safety, and Outcomes
February 2024
in “Plastic and Reconstructive Surgery – Global Open”
TLDR Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
This systematic review analyzed 12 randomized control trials involving 514 participants with androgenic alopecia, studying the efficacy and safety of autologous cellular and acellular stem cell–derived therapies. The stem cells were isolated from various sources including human adipose tissue, hair follicles, bone marrow, umbilical cord blood, and exfoliated deciduous teeth. The review found that these therapies can promote hair regeneration and density, although the outcomes may be temporary in some cases. Several studies reported significant increases in hair count, density, and thickness following treatments with different types of stem cells or their derivatives. The review concluded that both cellular and acellular stem cell–based therapies are a promising emerging solution for androgenic alopecia.
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