RU58841
| RU58841 at a glance | |
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Treatment |
The good: Potentially the most potent antiandrogen available, lots of studies show effectiveness. The bad: Expensive, grey market Bottom Line: Only for the brave and wealthy. Price Per Dose: $1.25+ USD
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RU58841 (PSK3841) is a non-steroidal DHT inhibitor antiandrogen. It is applied topically.
RU58841 was developed in France by Dr. Sewaya of the Roussel Uclaf Corporation. It's said to be one of the most potent antiandrogens available for topical use, yet does not seem to have any systemic absorption. If it lived up to the claims, this would be a holy grail for topical treatments.
Unfortunately, for unknown reasons, Roussel had not pursued marketing and approval for RU58841. This didn't stopp companies in other parts of the world from synthesizing the same chemical, however. One such company is Faith Eagle Lab in China. Quality and composition has not been verified at this time, but users report that the company sends the chemical in a powder form to be mixed at home. Because of purported instability when mixed, users typically make small batches when needed. [1]
Presently unverified: the rights to RU58841 were purchased by a Scottish company called ProStrakan. The drug is now officially referred to as PSK3841 and is in Phase II trials. ProStrakan's website currently only cites "Topical anti-androgen" as the research target. [2] [3]
[edit] Side Effects
Side effects are unknown.
[edit] See also
- Search for "RU58841" at: HairLossTalk.com, HairLossHelp.com, Hairsite.com
[edit] References
- A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice.
- RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.
- Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques.
- RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.
- Effects of topical antiandrogen and 5-alpha-reductase inhibitors on sebaceous glands in male fuzzy rats.
- Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaque.