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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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4.5 Month Progress (20M) – Can I expect more density and hairline regrowth?
General A 20-year-old has been using finasteride and minoxidil for 4.5 months, noticing reduced hair shedding and seeking advice on potential for increased hair density and hairline regrowth. They also use a dermaroller weekly but inconsistently. -
[Seeking Advice] 3.5 Years on Topical Fin/Min—Recent Regression. What’s next?
General A 24-year-old male experienced hair loss regression after 3.5 years on topical finasteride and minoxidil. He is considering switching to topical dutasteride or oral finasteride due to concerns about side effects and is seeking advice on the efficacy of these treatments. -
Is 1mg dutasteride enough?
General The user switched from finasteride to 1mg dutasteride daily due to continued hair loss and is also using minoxidil and rosemary oil. They are seeking advice on whether to increase the dutasteride dosage for better regrowth. -
Treatment suggestions (no systemic dht blockers)
Treatments A user is seeking hair loss treatments without using systemic DHT blockers like finasteride due to side effects. Suggestions include clascoterone (not FDA approved), pyrilutamide, RU58841, and low-dose topical finasteride, with a recommendation to consult a doctor. -
Norwood 2 or 2.5. What should I do?
General The user is considering starting minoxidil and finasteride for hair loss at Norwood 2 or 2.5. Another user suggests consulting a dermatologist and possibly using finasteride to prevent progression and minoxidil for regrowth, with dutasteride as an alternative. -
So many horror stories about switching from fin to dut
Finasteride/Dutasteride Switching from finasteride to dutasteride can cause initial shedding, but many see long-term hair regrowth and stabilization. Responses vary, with some experiencing fewer side effects and others finding it less effective.
New Featured Research
Effect of Platelet-Rich Plasma on Hair Follicle Growth in C57BL/6 Mice
The study investigated the effects of platelet-rich plasma (PRP) on hair follicle growth in 20 female C57BL/6 mice, divided into experimental and control groups. The experimental group received subcutaneous injections of PRP, while the control group received saline. Results showed that the experimental group experienced faster hair growth and higher expression of Wnt10b, a protein associated with hair follicle proliferation. This suggests that PRP promotes the proliferation of hair matrix and inner hair root sheath cells, accelerating the hair follicle cycle, making it a promising treatment for alopecia.
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New in research
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The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer
N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.
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The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer
N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.
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Significant Improvement With Ivarmacitinib After Suboptimal Response to Tofacitinib in Severe Alopecia Areata: A Case Report and Literature Review
Ivarmacitinib significantly improved hair regrowth in severe alopecia areata after tofacitinib was less effective.
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Comparative Efficacy of Oral Dutasteride and Low, Medium, and High-Dose Oral Minoxidil: A Six-Month Prospective Trichoscopic and Clinical Study
Oral minoxidil improved hair loss more than oral dutasteride.
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Establishing a Robust Preclinical Model to Investigate Early and Late Radiation-Induced Skin Reactions
The model effectively mimics radiation-induced skin damage for future research.
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Effective Topical Delivery of Minoxidil via Chitosan Coated Nanocapsules to Remodel Microenvironment of Dermal Follicle for Hair Regeneration
Chitosan-coated nanocapsules improve minoxidil delivery for better hair regrowth.
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Consensus Position Statement on Emerging Treatments in Dermatology by the Association of Cutaneous Surgeons of India Task Force
Most emerging dermatological treatments lack strong evidence and require more research.
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Use of Genetics in the Prediction of Success in Male Pattern Hair Loss Therapy and Mechanistic Studies
Genetics can help tailor treatments for male pattern hair loss, improving outcomes like stabilization or modest regrowth.
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Biomechanics of Chemically Treated Hair for Continuous 1D Strands
NaOH treatment improves hair strength and suitability for textiles.