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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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I changed the brand of min+fin and getting some shed need some guidance
General A 20-year-old male switched from MorrF5 to Zeelab’s MinoxilF, both containing minoxidil 5% and finasteride 0.1%, and is experiencing unexpected hair shedding. He is seeking guidance on whether the shedding is due to the brand change or if it's a normal reaction. -
Switched from FIN to DUT, hairline/temples worse
Finasteride/Dutasteride Switching from finasteride to dutasteride and oral minoxidil worsened hair thinning at the hairline and temples. The user is considering returning to finasteride, as dutasteride may not be effective for them. -
I aggregated hundreds of hair loss experiences. Here’s what actually shows up.
Research/Science Finasteride and minoxidil are commonly used for hair loss, with RU58841 and microneedling also showing effectiveness. Oral minoxidil and dutasteride are noted for their impact, while side effects and alternative treatments like ketoconazole and natural DHT blockers are discussed. -
2-year progress | Finasteride 1 mg oral daily + Minoxidil 5% topical nightly
Progress Pictures A 33-year-old experienced significant hair regrowth over two years using daily oral finasteride and topical minoxidil, with no noticeable side effects. Consistent treatment led to visible improvement in hair density. -
[32M] 4 months into 5mg fin and oral min. (Oct. ‘25 vs. Jan ‘26)
Progress Pictures A 32-year-old man experienced positive hair regrowth after 4 months using 1.2mg finasteride and 3mg oral minoxidil, with no side effects. He used a chewable combo pill from Hims, noting minoxidil aids regrowth and finasteride maintains hair. -
Wanting to reinstate finasteride, but still slightly anxious of PFS
General The user is anxious about potential side effects of finasteride, particularly PFS, and is considering reinstating it for hair loss treatment. They experienced anxiety-induced side effects previously and are seeking advice on overcoming their fear of restarting finasteride.
New Featured Research
Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway
This study identifies the AR/miR-128-3p/IGF-1 pathway as crucial in the dysfunction of hair follicle stem cells (HFSCs) in androgenetic alopecia (AGA). It finds that reduced IGF-1 expression impairs HFSCs activity, with AR activating miR-128-3p to suppress IGF-1. ASLNC168501, acting as a competing endogenous RNA, sequesters miR-128-3p, restoring IGF-1 levels. Overexpressing ASLNC168501 in dermal papilla cells enhances HFSCs' self-renewal and differentiation, reversing hair follicle atrophy in AGA mice, suggesting ASLNC168501 as a promising therapeutic target for AGA treatment.
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New in research
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What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
Androgenic alopecia is diagnosed by clinical evaluation and managed with treatments to stop hair loss and encourage regrowth.
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Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
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Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
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What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
Androgenic alopecia is diagnosed by clinical evaluation and managed with treatments to stop hair loss and encourage regrowth.
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A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
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Is There an Association Between 25(OH)D Serum Levels and Vitamin D Status with the Severity of Androgenetic Alopecia in Men?
Lower vitamin D levels are linked to more severe hair loss in men.
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A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
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Development of Herbal Hair Wax Stick With Scalp Nourishing Extract
The herbal hair wax stick is a safe and effective natural alternative to synthetic hair products.
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Development of Herbal Hair Wax Stick With Scalp Nourishing Extract
The herbal hair wax stick is a safe and effective natural alternative to synthetic styling products.