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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Anyone experienced sleep side effects that improve on fin?
Finasteride The user has been taking 1mg of finasteride every other day for two months, experiencing improved hair quality but disrupted sleep. They are seeking advice on whether the sleep issues will improve with continued use or if they should stop the medication. -
M25 Dutasteride is the best thing that ever happened to me
Update A 25-year-old switched from finasteride to dutasteride, experiencing significant hair regrowth and improved hair quality after 6 months, taking it three times a week. The user stopped finasteride entirely, citing dutasteride's longer half-life as more effective. -
25 years on Finasteride and it's not working anymore.
Finasteride/Dutasteride A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT. -
Day 1 vs 1 month vs 4 months vs 6 months vs 1 year vs 1 year 3 months (My story)
Progress Pictures A 23-year-old experienced hair regrowth using 1mg finasteride and 5mg oral minoxidil after initial shedding, but noticed hair loss after stopping minoxidil and starting vaping. They resumed oral minoxidil and finasteride, attributing hair loss to nicotine and stopping minoxidil, and are considering additional treatments like dutasteride. -
19M should i start fin?
General A 19-year-old experiencing diffuse thinning on the top of the head has seen some improvement with ketoconazole but is considering starting finasteride. They are seeking advice on whether to begin this treatment as they approach their 20th birthday. -
15years fin user switching to dut
Finasteride/Dutasteride A long-term finasteride user is considering switching to dutasteride due to hair loss progression. Users share experiences with switching, noting side effects and varying effectiveness, with some experiencing shedding and others maintaining their hairline.
New Featured Research
Nanozyme Catalysis Restores Hair Follicle Integrity by Reversing Peroxisomal Collapse.
This study identifies peroxisomal dysfunction as a key factor in hair follicle degeneration and alopecia, highlighting its role in disrupting metabolic and oxidative processes. Researchers found that peroxisome-associated pathways were downregulated in alopecia patients, and similar dysfunctions were observed in <i>Nudt7</i>-deficient mice, leading to hair thinning and oxidative stress. To counteract this, catalytic nanozymes (HA-Hem) were developed to mimic peroxisomal catalase activity, restoring metabolic balance and promoting hair regeneration in murine models. Nanozyme treatment enhanced PPARα expression, improving peroxisomal and mitochondrial function and outperforming minoxidil in regenerative efficacy. These results suggest that targeting peroxisomal function could be a promising therapeutic strategy for alopecia.
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New in research
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The Genetic Basis of Dermatophytosis Skin Infection Susceptibility
Genetic factors, skin barrier, immune function, and obesity influence risk of fungal skin infections.
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Serum Ferritin and Hair Iron Content in Correlation to Hair Diameter and Density: A Case-Control Study
Hair iron levels might help increase hair thickness in early hair loss.
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Successful Hair Regrowth in Early Frontal Fibrosing Alopecia With Combination Therapy
Early combination therapy can effectively regrow hair in frontal fibrosing alopecia.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Efficacy of Intraoperative Platelet-Rich Plasma in Follicular Unit Extraction Hair Transplantation: A Prospective Study
Using PRP in hair transplants improves hair regrowth, healing, and patient satisfaction.
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Traditional Review: Exosomes in Dermatology and Cosmetology
Exosomes show promise for treating skin conditions and improving cosmetic skin health.
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High-Throughput Screening of Small Molecule Wnt/β-Catenin Activators for Hair and Nail Growth
Certain compounds can boost hair and nail growth.
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Beyond Hair Preservation: Scalp Cooling as a Biopsychosocial Intervention in Patients Receiving Highly Alopecia-Inducing Chemotherapy
Scalp cooling helps prevent hair loss and improves quality of life during chemotherapy.