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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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My progress from October of last year. My routine below ⬇️
Is this regrowth? The user started using topical minoxidil, oral finasteride, GHK-CU, and HGH in October, resulting in thicker hair and improved overall health. They experienced minor side effects like dehydration from HGH but reported benefits like clearer skin, better recovery, and muscle gain. -
4.5 Month Progress (20M) – Can I expect more density and hairline regrowth?
General A 20-year-old has been using finasteride and minoxidil for 4.5 months, noticing reduced hair shedding and seeking advice on potential for increased hair density and hairline regrowth. They also use a dermaroller weekly but inconsistently. -
Minoxidil: How It Changes the Scalp Hormone Environment
Research/Science Minoxidil increases blood supply to the scalp, strengthening dormant follicles and extending the growth phase, but may increase scalp activity that can be countered with DHT blockers. Women experiencing side effects from finasteride or dutasteride for hair loss might consider alternatives like estrogen, especially if on birth control. -
[Seeking Advice] 3.5 Years on Topical Fin/Min—Recent Regression. What’s next?
General A 24-year-old male experienced hair loss regression after 3.5 years on topical finasteride and minoxidil. He is considering switching to topical dutasteride or oral finasteride due to concerns about side effects and is seeking advice on the efficacy of these treatments. -
Is 1mg dutasteride enough?
General The user switched from finasteride to 1mg dutasteride daily due to continued hair loss and is also using minoxidil and rosemary oil. They are seeking advice on whether to increase the dutasteride dosage for better regrowth. -
Treatment suggestions (no systemic dht blockers)
Treatments A user is seeking hair loss treatments without using systemic DHT blockers like finasteride due to side effects. Suggestions include clascoterone (not FDA approved), pyrilutamide, RU58841, and low-dose topical finasteride, with a recommendation to consult a doctor.
New Featured Research
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments
The narrative review on androgenetic alopecia in women explores the condition's pathophysiology, clinical evaluation, and treatment options. It highlights spironolactone as a common and effective treatment, while also discussing the use of finasteride and dutasteride, though their effectiveness in postmenopausal women is uncertain. The review introduces clascoterone, a new topical treatment, and notes the promising results of combining low-dose oral minoxidil with spironolactone. The importance of personalized treatment plans and further research to enhance therapeutic strategies for women with androgenetic alopecia is emphasized.
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New in research
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Targeting the Gut Microbiota with Probiotics and Postbiotics: Emerging Strategies Against Alopecia
Modifying gut bacteria with pro- and postbiotics may help treat hair loss.
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The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer
N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.
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The N-K Healing Series: Complete Geometric Restoration for Wounds, Pain, and Burns Using N-K Universal Computer
N-K Geometric Medicine heals wounds, pain, and burns better and faster than current treatments, without side effects.
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Significant Improvement With Ivarmacitinib After Suboptimal Response to Tofacitinib in Severe Alopecia Areata: A Case Report and Literature Review
Ivarmacitinib significantly improved hair regrowth in severe alopecia areata after tofacitinib was less effective.
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Effect of Platelet-Rich Plasma on Hair Follicle Growth in C57BL/6 Mice
Platelet-rich plasma (PRP) speeds up hair growth in mice.
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Comparative Efficacy of Oral Dutasteride and Low, Medium, and High-Dose Oral Minoxidil: A Six-Month Prospective Trichoscopic and Clinical Study
Oral minoxidil improved hair loss more than oral dutasteride.
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Establishing a Robust Preclinical Model to Investigate Early and Late Radiation-Induced Skin Reactions
The model effectively mimics radiation-induced skin damage for future research.
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Effective Topical Delivery of Minoxidil via Chitosan Coated Nanocapsules to Remodel Microenvironment of Dermal Follicle for Hair Regeneration
Chitosan-coated nanocapsules improve minoxidil delivery for better hair regrowth.
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Consensus Position Statement on Emerging Treatments in Dermatology by the Association of Cutaneous Surgeons of India Task Force
Most emerging dermatological treatments lack strong evidence and require more research.