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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Scalp itching on fin for 2 years need hellppp
General The user has been experiencing severe scalp itching and red spots after using finasteride for two years, suspecting possible allergies or a fungal infection. Despite trying ketoconazole shampoo and stopping saw palmetto supplements, the symptoms persist, leading to increased hair loss. -
How can ketoconazole shampoo block androgen receptor if it's just washed off?
Ketoconazole Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hair loss are minimal compared to treatments like finasteride. -
Started minoxidil but very afraid and reluctant to start finasteride
General A 22-year-old is using minoxidil for hair loss but is hesitant to start finasteride due to mixed advice and fear of side effects. They seek guidance on whether to begin finasteride despite concerns about potential permanent side effects. -
Switch to dut or increase to 1mg fin?
Treatments The user has been using 0.5mg finasteride daily for two years without side effects but is considering switching to dutasteride or increasing finasteride to 1mg for better results. They are unsure whether to proceed with dutasteride or increase the finasteride dosage. -
Large Dandruff Flakes Causing Hair Loss
General A 23-year-old male is experiencing large dandruff flakes causing hair loss, despite using anti-dandruff shampoo. He seeks advice on resolving the issue, noting a family history of baldness. -
Weird hair loss pattern, localized on the front of my scalp, what gives?
General The user is experiencing significant hair thinning on the front scalp while taking oral finasteride and minoxidil. They are unsure if it's androgenetic alopecia or related to seborrheic dermatitis.
New Featured Research
Phenytoin or Spironolactone Intervention Counteracts 5-Fluorouracil–Induced Alopecia in Rats by Suppressing Oxidative Stress and Inflammation While Promoting Collagen Synthesis
This study explored the effects of phenytoin and spironolactone on 5-fluorouracil (5-FU)–induced alopecia in rats, a model for chemotherapy-induced hair loss. Both treatments significantly counteracted the negative effects of 5-FU, such as weight loss, reduced appetite, and hair loss, by reducing oxidative stress and inflammation. Phenytoin and spironolactone improved hair regrowth and restored follicular health, with spironolactone showing a more pronounced effect on hair regrowth and collagen organization. These findings indicate that phenytoin and spironolactone could be effective in mitigating chemotherapy-induced alopecia and improving recovery and quality of life post-treatment.
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New in research
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Using the Mechanisms of Action Involved in the Pathogenesis of Androgenetic Alopecia to Treat Hair Loss
Combining different drugs can improve hair loss treatment.
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Amitriptyline-Induced Telogen Effluvium in a Patient with Cervical Disc Prolapse: A Case Report
Amitriptyline can cause temporary hair loss, which stops after discontinuing the drug.
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Quercetin Promotes Production of Secondary Hair Follicle Stem Cells in Cashmere Goat: A Mechanistic Study
Quercetin boosts hair follicle stem cell growth and survival in cashmere goats.
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Dermatological Alterations Induced by Gynecological Hormonal Imbalances: Acne, Hirsutism, and Alopecia
Hormonal imbalances can cause acne, excess hair growth, and hair loss in women, needing combined medical and emotional care.
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Hyperandrogenism Insulin Resistance-Acanthosis Nigricans Syndrome in a Female Adolescent with Migraine: A Case Report
Early diagnosis and treatment of endocrine disorders like HAIR-AN syndrome can improve outcomes in adolescents.
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Psoriasis and Alopecia: Unveiling the Links
Psoriasis patients are more likely to develop alopecia areata due to complex autoimmune interactions.
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Effects of GLP-1 Receptor Agonists on Hair Loss and Regrowth: A Systematic Review
GLP-1 receptor agonists may cause hair loss, but regrowth is rare.
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Associations Between GLP-1 Receptor Agonists and Alopecia: A Multi-Center Retrospective Analysis and Public Interest Trends
GLP-1 receptor agonists may increase the risk of a specific type of hair loss called androgenetic alopecia.
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Prevalence and Hormonal Profiling of Secondary Amenorrheic Patients Presenting to a Fertility Clinic – An Observational Study
Hyperprolactinemia is the most common cause of secondary amenorrhea, followed by drug use.