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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Is this Progress? - NW7 Diffuse going for the comeback. (49M)
Progress Pictures A 49-year-old is using finasteride, minoxidil, tretinoin, and ketoconazole shampoo to combat advanced hair loss and hopes for enough regrowth to consider a hair transplant. Progress is slow, but some improvement is noted by others. -
Anyone experienced sleep side effects that improve on fin?
Finasteride The user has been taking 1mg of finasteride every other day for two months, experiencing improved hair quality but disrupted sleep. They are seeking advice on whether the sleep issues will improve with continued use or if they should stop the medication. -
End of Hair loss ( AGA ) ? Since they produce it in china probably we don’t need to wait other 10 yrs😁
Treatment GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective. -
M25 Dutasteride is the best thing that ever happened to me
Update A 25-year-old switched from finasteride to dutasteride, experiencing significant hair regrowth and improved hair quality after 6 months, taking it three times a week. The user stopped finasteride entirely, citing dutasteride's longer half-life as more effective. -
25 years on Finasteride and it's not working anymore.
Finasteride/Dutasteride A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT. -
Day 1 vs 1 month vs 4 months vs 6 months vs 1 year vs 1 year 3 months (My story)
Progress Pictures A 23-year-old experienced hair regrowth using 1mg finasteride and 5mg oral minoxidil after initial shedding, but noticed hair loss after stopping minoxidil and starting vaping. They resumed oral minoxidil and finasteride, attributing hair loss to nicotine and stopping minoxidil, and are considering additional treatments like dutasteride.
New Featured Research
Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of FP-receptor activation
This pilot proof-of-concept trial investigated the effects of topical latanoprost acid on female androgenetic alopecia. Conducted with adult women, the study tested three concentrations (0.01%, 0.05%, and 0.1%) over 6 months. The 0.05% concentration showed the most consistent improvement in target-area hair count, with an average increase of 23.5 hairs/cm², along with reduced yellow dots and a shift to multi-hair follicular units. Safety was favorable, with no serious adverse events. Mechanistic assays indicated that latanoprost acid triggered rapid, concentration-dependent Ca²⁺ flux in human hair dermal papilla cells. These findings support further trials focusing on the 0.05% concentration.
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New in research
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Nanozyme Catalysis Restores Hair Follicle Integrity by Reversing Peroxisomal Collapse
Nanozymes can restore hair growth by fixing peroxisomal function.
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Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis
The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
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The Genetic Basis of Dermatophytosis Skin Infection Susceptibility
Genetic factors, skin barrier, immune function, and obesity influence risk of fungal skin infections.
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Serum Ferritin and Hair Iron Content in Correlation to Hair Diameter and Density: A Case-Control Study
Hair iron levels might help increase hair thickness in early hair loss.
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Successful Hair Regrowth in Early Frontal Fibrosing Alopecia With Combination Therapy
Early combination therapy can effectively regrow hair in frontal fibrosing alopecia.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Beyond Hair Preservation: Scalp Cooling as a Biopsychosocial Intervention in Patients Receiving Highly Alopecia-Inducing Chemotherapy
Scalp cooling helps prevent hair loss and improves quality of life during chemotherapy.
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High-Throughput Screening of Small Molecule Wnt/β-Catenin Activators for Hair and Nail Growth
Certain compounds can boost hair and nail growth.