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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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19M should i start fin?
General A 19-year-old experiencing diffuse thinning on the top of the head has seen some improvement with ketoconazole but is considering starting finasteride. They are seeking advice on whether to begin this treatment as they approach their 20th birthday. -
Minoxidil Question (effectiveness taking orally & topically)
Minoxidil Taking minoxidil both orally and topically may improve results, but consistency with topical application might not be as crucial if oral intake is regular. Microneedling is also considered for additional benefits. -
M26 Regrowth Journal [0.5mg dut + 5mg oral minoxidil]
Journals / Progress Pictures A 26-year-old male is documenting his hair regrowth journey using 0.5mg dutasteride and 5mg oral minoxidil, transitioning from 5% topical minoxidil. He reports no significant side effects after one week, except for slight water retention and increased libido. -
3 months on Fin/Min oral chewable
Progress Pictures The user experienced positive hair regrowth and thicker hair after 12 weeks on 1.25mg Finasteride and 2.5mg Minoxidil chewables, with no side effects. They plan to reassess the need for a hair transplant after seeing further progress. -
Temple regrowth, 5 months on fin + min
Progress Pictures A trans man shared his 5-month progress using finasteride and minoxidil for temple regrowth, noting slow but steady results. Despite some negative comments, he received support and encouragement from others, with advice to start treatment early for best results. -
Is it time or should I hold on? *Edit
General The user is considering whether to continue with hair loss treatments or change their hairstyle, having previously experienced side effects from finasteride. They are open to trying other options and seeking advice.
New Featured Research
Nanozyme Catalysis Restores Hair Follicle Integrity by Reversing Peroxisomal Collapse.
This study identifies peroxisomal dysfunction as a key factor in hair follicle degeneration and alopecia, highlighting its role in disrupting metabolic and oxidative processes. Researchers found that peroxisome-associated pathways were downregulated in alopecia patients, and similar dysfunctions were observed in <i>Nudt7</i>-deficient mice, leading to hair thinning and oxidative stress. To counteract this, catalytic nanozymes (HA-Hem) were developed to mimic peroxisomal catalase activity, restoring metabolic balance and promoting hair regeneration in murine models. Nanozyme treatment enhanced PPARα expression, improving peroxisomal and mitochondrial function and outperforming minoxidil in regenerative efficacy. These results suggest that targeting peroxisomal function could be a promising therapeutic strategy for alopecia.
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New in research
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Serum Ferritin and Hair Iron Content in Correlation to Hair Diameter and Density: A Case-Control Study
Hair iron levels might help increase hair thickness in early hair loss.
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The Genetic Basis of Dermatophytosis Skin Infection Susceptibility
Genetic factors, skin barrier, immune function, and obesity influence risk of fungal skin infections.
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Successful Hair Regrowth in Early Frontal Fibrosing Alopecia With Combination Therapy
Early combination therapy can effectively regrow hair in frontal fibrosing alopecia.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Low-Dose Oral Minoxidil And Topical Minoxidil: Consensus Recommendations For Managing Male And Female Pattern Hair Loss In Hair Transplant Patients Using A Modified Delphi Process
Low-dose oral and topical minoxidil are recommended for managing hair loss in transplant patients, with specific doses and precautions.
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Beyond Hair Preservation: Scalp Cooling as a Biopsychosocial Intervention in Patients Receiving Highly Alopecia-Inducing Chemotherapy
Scalp cooling helps prevent hair loss and improves quality of life during chemotherapy.
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Efficacy of Intraoperative Platelet-Rich Plasma in Follicular Unit Extraction Hair Transplantation: A Prospective Study
Using PRP in hair transplants improves hair regrowth, healing, and patient satisfaction.
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Traditional Review: Exosomes in Dermatology and Cosmetology
Exosomes show promise for treating skin conditions and improving cosmetic skin health.
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High-Throughput Screening of Small Molecule Wnt/β-Catenin Activators for Hair and Nail Growth
Certain compounds can boost hair and nail growth.