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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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22M Losing hair since 16, nothing helps, scalp always itchy. Just fed up.
Treatment A 22-year-old experiencing hair loss and persistent scalp itchiness since age 16 has tried various treatments, including finasteride, ketoconazole shampoo, and dietary changes, with no success. Suggestions include consulting a knowledgeable dermatologist, considering seborrheic dermatitis, and trying different shampoos like Selsun Blue or those with selenium sulfide. -
6 Months on Oral Fin + Oral Minoxidil
Progress Pictures A user shared their 6-month progress using oral finasteride and oral minoxidil for hair loss, reporting significant improvements with minimal side effects, such as slight erectile dysfunction that resolved. Other users discussed their experiences, concerns about side effects, and the effectiveness of these treatments. -
Severe Fin side effects, what other options do I have?
General The user experienced severe side effects from finasteride, including panic attacks and suicidal thoughts, and is seeking alternative hair loss treatments. They have been using oral finasteride and topical minoxidil. -
Scientists have uncovered a simple way to cure hair loss – as incredible before–and–after photos show the results in just 8 weeks
Research/Science Scientists claim a combination of caffeine, two proteins, and Centella asiatica extracts can cure hair loss, but skepticism remains due to past unfulfilled promises. Users discuss various treatments like minoxidil, finasteride, and microneedling, expressing doubt about the effectiveness of new methods. -
Dutasteride results after 1 year and a few months
Progress Pictures Switching from finasteride to dutasteride led to significant hair regrowth and thickening for the user, who also uses ketoconazole shampoo. The user experienced increased libido and encourages others not to be discouraged by negative opinions about dutasteride. -
Why is the general consensus that if you can’t tolerate 5AR Inhibitors you’re “cooked”?
Research/Science Alternatives to finasteride for hair loss include minoxidil, alfatrodial, fluridil, pyrilutamide, and Nizoral. These treatments may not be as effective as finasteride but can help slow hair loss progression.
New Featured Research
A Review On Minoxidil a Potent Hair growth Agent
Minoxidil, initially an antihypertensive drug, is now widely used for treating androgenetic alopecia due to its hair growth-promoting side effect. Although its exact mechanism is not fully understood, it is thought to enhance blood flow to hair follicles, prolong the anagen phase, stimulate dermal papilla cells, and upregulate VEGF. Clinical trials indicate that both 2% and 5% minoxidil solutions significantly increase hair density, with the 5% solution being more effective. Serum-based formulations improve scalp penetration and reduce irritation, but continuous use is necessary to maintain results, and some users may experience scalp irritation. Combining synthetic and herbal ingredients in hair serums is a promising strategy for managing hair loss and enhancing hair health.
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New in research
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Lupus Pneumonitis Masquerading as Community Acquired Pneumonia and Pulmonary Tuberculosis: A Case Report
Lupus pneumonitis can be misdiagnosed as pneumonia or tuberculosis, so consider lupus in similar cases for proper treatment.
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Telogen Effluvium and Metabolic Stress in Modern Weight Loss Interventions: A Narrative Clinical Review
Hair loss from weight-loss treatments is usually temporary and reversible.
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Efficacy of Platelet-Rich Plasma as an Adjunct to Hair Transplantation: A Systematic Review
PRP may improve hair transplant results, but more research is needed.
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Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
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A Phosphoinositide-Mediated Switch of GET Pathway Receptor Dimerization in Arabidopsis
Phospholipids help plant proteins move by regulating receptor interactions.
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Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia
Stevioside-based microneedles improve minoxidil delivery and hair growth for treating hair loss.
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Comparing Single Spin Versus Double Spin Techniques of Platelet Rich Plasma Preparation in Treating Male Androgenetic Alopecia: A Prospective Study
Both single and double spin PRP methods effectively treat male hair loss, but single spin is easier and cheaper.
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Comparing Minoxidil-Finasteride Mixed Solution With Minoxidil Solution Alone for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The minoxidil-finasteride combination is more effective for hair growth than minoxidil alone.
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Impact of Finasteride on Serum PSA Levels in Men With Benign Prostatic Hyperplasia: A Systematic Review
Finasteride lowers PSA levels and prostate size, requiring adjusted PSA interpretation for accurate cancer screening.