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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Can this be fixed
General A 24-year-old noticed hair thinning over 4-6 years and is seeking advice on whether it can be salvaged. Treatments mentioned include Minoxidil, finasteride, and RU58841. -
Hair loss over last 3 years plan of action review
General The user is experiencing hairline recession and plans to use minoxidil, finasteride, and biotin for a year, considering a hair transplant if needed. They seek advice on their treatment plan and additional ways to support hair growth. -
Testosterone and Estradiol levels on 1 mg/day dutasteride
Finasteride/Dutasteride A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015. -
1 year of treatment + frontal transplant = life-changing results.
Progress Pictures A 30-year-old shared their successful hair restoration journey using a combination of liposomal topical finasteride and minoxidil, vitamins, and a second hair transplant in Greece, resulting in life-changing improvements without side effects. The user emphasized the importance of proper research for hair transplant clinics and expressed gratitude for finding an effective treatment protocol. -
19M with Diffuse and Crown Thinning: Start Minoxidil or Seek Second Opinion?
General A 19-year-old male with diffuse and crown thinning is considering starting minoxidil as advised by a dermatologist but is unsure if he should seek a second opinion. Another user suggests consulting a reputable dermatologist to avoid wasting resources. -
Should I Split 1mg Finasteride or Take 1mg Every Other Day?
Finasteride The conversation is about whether to split 1mg finasteride pills to take 0.5mg daily or take 1mg every other day to save money and reduce side effects. There are concerns about the effectiveness of splitting due to the pill's coating and alternating due to its half-life.
New Featured Research
A Review On Minoxidil a Potent Hair growth Agent
Minoxidil, initially an antihypertensive drug, is now widely used for treating androgenetic alopecia due to its hair growth-promoting side effect. Although its exact mechanism is not fully understood, it is thought to enhance blood flow to hair follicles, prolong the anagen phase, stimulate dermal papilla cells, and upregulate VEGF. Clinical trials indicate that both 2% and 5% minoxidil solutions significantly increase hair density, with the 5% solution being more effective. Serum-based formulations improve scalp penetration and reduce irritation, but continuous use is necessary to maintain results, and some users may experience scalp irritation. Combining synthetic and herbal ingredients in hair serums is a promising strategy for managing hair loss and enhancing hair health.
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New in research
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Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
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Efficacy of Platelet-Rich Plasma as an Adjunct to Hair Transplantation: A Systematic Review
PRP may improve hair transplant results, but more research is needed.
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Comparing Single Spin Versus Double Spin Techniques of Platelet Rich Plasma Preparation in Treating Male Androgenetic Alopecia: A Prospective Study
Both single and double spin PRP methods effectively treat male hair loss, but single spin is easier and cheaper.
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Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia
Stevioside-based microneedles improve minoxidil delivery and hair growth for treating hair loss.
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Comparing Minoxidil-Finasteride Mixed Solution With Minoxidil Solution Alone for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The minoxidil-finasteride combination is more effective for hair growth than minoxidil alone.
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Herbal Ingredients for Hair Care Product Development
Herbal ingredients are effective and safer for treating hair issues and promoting growth.
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Comparative Efficacy of Topical Chitosan and Minoxidil in Hair Loss: A Controlled Study With Microneedling
Chitosan and minoxidil both improve hair growth, but more research is needed on chitosan.
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Non-Surgical Hair Restoration
Non-surgical treatments for hair loss are becoming more advanced and personalized.
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Effective Multimodal Therapy for Chemically Aggravated Androgenetic Alopecia: A Case Report Using PRP and Mesotherapy
Combining PRP and mesotherapy effectively improved hair density and scalp health in a patient with severe hair loss.