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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Dutasteride. What next?
General A 31-year-old male switched from finasteride to oral dutasteride (0.5mg, 2x a week) and uses liquid minoxidil daily for hair loss. He experienced shedding and regrowth but is considering increasing dutasteride to 3x a week due to concerns about hair density and ongoing issues. -
Story time! The Great Unbalding (PP405)
Research/Science PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials. -
People who don’t microneedle, why?
Microneedling Microneedling is often combined with minoxidil for hair growth, but concerns about scalp damage, pain, and effectiveness deter some users. Alternatives like finasteride, dutasteride, tretinoin, and laser treatments are preferred by others. -
4 years on fin and min (Before and After) Age 27 to 31
Progress Pictures A user experienced significant hair regrowth using finasteride and minoxidil over four years, despite side effects like seborrheic dermatitis, urinary changes, and water retention. They were satisfied with the results and maintained a strong physique. -
Can finasteride 5mg be cut into one-fifth and taken to treat hair loss?
Finasteride Finasteride 5mg tablets can be cut into one-fifth to treat hair loss. This method is considered due to cost concerns. -
7m 20d progress, is this good?
Is this regrowth? The user has experienced noticeable hair regrowth after 7 months and 20 days using finasteride, minoxidil, dermastamping, vitamin D, zinc, and ketoconazole shampoo. The user reports improved hairline and self-esteem with no side effects.
New Featured Research
Preferential Crosstalk between Perifollicular Capillary Vessels and Dermal Papilla Cells during Hair Cycling Homeostasis
This study highlights the dynamic role of perifollicular vascularization in hair cycling homeostasis, emphasizing the preferential mobilization of capillary vessels around the dermal papilla (DP). Minoxidil treatment enhanced this mobilization, while aging models showed inhibition. Vascular endothelial cells induced angiogenic chemokine expression, such as CCL2, in DP cells, enhancing vessel-DP crosstalk. CCL2 levels fluctuated with hair cycles and decreased in aged skin, with CCL2-neutralizing antibodies reducing vascularization and DP function. These findings suggest that enhancing vessel-DP interactions could be a therapeutic target for hair loss and skin aging.
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New in research
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Assessment of Efficacy of Platelet-Rich Plasma Augmentation in Follicular Unit Extraction for Hair Density Improvement: A Prospective Study
PRP significantly improves hair density and satisfaction in hair restoration.
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A Review On Minoxidil: A Potent Hair Growth Agent
Minoxidil effectively promotes hair growth, especially in a 5% solution, but requires continuous use.
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Lupus Pneumonitis Masquerading as Community Acquired Pneumonia and Pulmonary Tuberculosis: A Case Report
Lupus pneumonitis can be misdiagnosed as pneumonia or tuberculosis, so consider lupus in similar cases for proper treatment.
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Telogen Effluvium and Metabolic Stress in Modern Weight Loss Interventions: A Narrative Clinical Review
Hair loss from weight-loss treatments is usually temporary and reversible.
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Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
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A Phosphoinositide-Mediated Switch of GET Pathway Receptor Dimerization in Arabidopsis
Phospholipids help plant proteins move by regulating receptor interactions.
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Efficacy of Platelet-Rich Plasma as an Adjunct to Hair Transplantation: A Systematic Review
PRP may improve hair transplant results, but more research is needed.
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Comparing Single Spin Versus Double Spin Techniques of Platelet Rich Plasma Preparation in Treating Male Androgenetic Alopecia: A Prospective Study
Both single and double spin PRP methods effectively treat male hair loss, but single spin is easier and cheaper.
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Natural Sweetener Stevioside-Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia
Stevioside-based microneedles improve minoxidil delivery and hair growth for treating hair loss.