research Spheroid Cell Cultures as a Promising Study Model for Hair Follicle Regeneration
Culturing Dermal Papilla Cells and Hair Follicle Stem Cells in 3D conditions can significantly improve hair regeneration potential.
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research Mimicking Hair Disorders by Genetic Manipulation of Organ-Cultured Human Hair Follicles
Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
research The Negative Regulator CXXC5: Making WNT Look a Little Less Disheveled
CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.
research Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling
The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
research The Variable Cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research A Review: Pharmacological Activities of Quinoline Alkaloids of Cinchona Species
Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.
research Faculty Opinions Recommendation of FGF9 from Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding
FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
research Inhibition of Wnt/β-Catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury
Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
research Epithelial Stem Cells And Implications For Wound Repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research Valproic Acid and Alopecia: A Two-Edged Sword
Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
research After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and WNT7b to Promote Regeneration
Double stranded RNA helps skin wounds heal by coordinating specific proteins and signaling pathways.
research Urotensin II Promotes the Proliferation and Secretion of Vascular Endothelial Growth Factor in Rat Dermal Papilla Cells by Activating the Wnt-Beta-Catenin Signaling Pathway
Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.
research SB216763-Loaded Multifunctional Copper-Doped Bioglass 3D Printed Scaffold Promotes Wound Healing and Functional Skin Regeneration
The 3D printed scaffold with SB216763 and copper helps heal wounds and regrow skin and hair.
research Research Advances on the Mechanism of Wnt/Beta-Catenin Signaling Pathway in Body Surface Wound Healing
The Wnt/β-catenin signaling pathway is important for skin wound healing and affects inflammation, cell growth, and other healing processes.
research Skin Fibroblast Heterogeneity and Plasticity Are Determined by the Local Niche
Mouse skin fibroblasts vary in function and adaptability based on their environment.
research LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells
H19 boosts hair growth potential by activating Wnt signaling, possibly helping treat hair loss.
research Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice
The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.
research Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration
Hydrogel microcapsules help create cells that boost hair growth.
research Divergent Molecular Signatures of Regeneration and Fibrosis During Wound Repair
Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
research Advances in Hair Growth
The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
research Stem Cell Dynamics, Migration, and Plasticity During Wound Healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research Effects of CO2 Fractional Laser on Hair Growth in C57BL/6 Mice and Potential Underlying Mechanisms
CO2 fractional laser therapy may help regrow hair without scarring by affecting certain inflammatory and growth-related molecules.
research Peer Review of Secreted Frizzled-Related Protein 4 Inhibiting Hair Follicle Regeneration
sFRP4 partially inhibits hair regeneration, but the study needs clearer data analysis and better explanation of the process.
research Multi-Tasking Epidermal Stem Cells: Beyond Epidermal Maintenance
Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
research Building a Functional Niche for Hair Follicle Stem Cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling
Activating PKM2 and Wnt/β-catenin signaling together can potentially enhance hair growth and could be a treatment for hair loss.
research Interest of Silybum Marianum Extract, Manganese PCA, and Lespedeza Capitata Extract in a New Anti-Hair Loss Serum to Stimulate Hair Growth and Prolong Anagen Phase
The extract of Silybum marianum, Manganese PCA, and Lespedeza capitata can boost hair growth and extend the growth phase when combined in a serum.
research Hair Growth Control by Innate Immunocytes: Perifollicular Macrophages Revisited
Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.