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Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

SHBG may be a useful early indicator and treatment target for PCOS.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Vitamin D receptor is crucial for starting hair growth after birth.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Pregnancy can cause normal skin changes that usually go away after childbirth and don't need treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.