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Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

New genes and pathways are important for testosterone production and male sexual development.

Vitamin D3 affects cell differentiation in specific skin areas.

Understanding how fetal wounds heal could help improve healing in adults.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.