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Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Targeting the skin's endocannabinoid system could help treat skin disorders.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Notch-related genes play a key role in the development and cycling of hair follicles.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.