208 citations,
January 2013 in “Lab on a Chip” The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
162 citations,
August 2004 in “Journal of Investigative Dermatology” Hair loss causes stress and affects mental health; treatment and support needed.
132 citations,
July 2000 in “Lupus” In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
123 citations,
September 1987 in “JAMA” IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
119 citations,
June 1993 in “BMJ” Alopecia is a key indicator of thallium poisoning.
114 citations,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
106 citations,
December 2015 in “Journal of The American Academy of Dermatology” Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.
106 citations,
July 2013 in “Advances in wound care” UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
102 citations,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
86 citations,
May 2005 in “Seminars in Arthritis and Rheumatism” Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.
74 citations,
July 1979 in “Lancet” Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
73 citations,
May 1976 in “JAMA” Long-term parenteral nutrition without zinc can cause severe zinc deficiency.
72 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
68 citations,
May 2013 in “The American journal of medicine” Traditional Chinese medicines with heavy metals can cause severe poisoning.
65 citations,
May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
63 citations,
December 2002 in “Archives of Dermatology” The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
62 citations,
April 2008 in “Neurobiology of aging” Scientists found a gene in mice that causes early hearing loss.
61 citations,
March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
50 citations,
February 2018 in “Biomedicine & pharmacotherapy” Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
50 citations,
June 1999 in “Annals of Oncology” Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.
49 citations,
March 2018 in “Toxicological sciences” Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
47 citations,
July 2005 in “British Journal of Dermatology” Topical vitamin D3 does not prevent hair loss from chemotherapy.
45 citations,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
42 citations,
May 2013 in “Oral Diseases” Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
42 citations,
January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
40 citations,
November 2016 in “Molecules” Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.
40 citations,
July 1995 in “Toxicologic Pathology” Minoxidil can harm dog's heart.
39 citations,
January 1994 in “European Journal of Cancer” Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.