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TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Finasteride-loaded nanoparticles may help treat alopecia.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

New treatments for male hypogonadism are effective and should be personalized.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.