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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

BMP2 and BMP7 have opposite roles in feather formation.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Prolactin affects when mice shed and grow hair.

New genes and pathways are important for testosterone production and male sexual development.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Bimatoprost, a glaucoma medication, may also help treat hair loss.