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Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Stress can stop hair growth in mice, and treatments can reverse this effect.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Skin-derived precursors in hair follicles come from different origins but function similarly.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Nerves and chemicals in the body can affect hair growth and loss.

Voriconazole can cause serious side effects, especially in long-term use.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.