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Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.

An HIV patient with IRIS had rare syphilis symptoms affecting skin, eyes, and nerves.

Aralia continentalis root extract may help with hair growth.

Korean ginseng berry may help with hair regrowth.

HIV-positive patients, especially men who have sex with men, had a high rate of skin diseases and sexually transmitted infections.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Optimized film improves finasteride skin absorption and treatment efficiency.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.

Using micro skin tissue columns improves skin wound healing and reduces scarring.

Skin RAGE levels are linked to inflammation and cell death.

HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.

Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Skin stem cells can help improve skin repair and regeneration.

Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.