research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
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research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Efficacy of Imiquimod 5% Cream in the Treatment of Equine Sarcoids: A Pilot Study
Imiquimod 5% cream reduced equine sarcoids in most cases.
research A Review on Jasmonic Acid and Its Derivatives
Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
research The Naked Truth: Sphynx and Devon Rex Cat Breed Mutations in KRT71
Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
research Menstrual Disorders in Adolescents
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research Biotin-Responsive Alopecia and Developmental Regression
Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
research A Clinical Overview of Hair Removal Using Lasers and Light Sources
Lasers and light sources can effectively remove hair, work best on fair skin with dark hair, and usually need multiple treatments.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation
The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
research Recent Advances in Microneedle Composites for Biomedical Applications: Advanced Drug Delivery Technologies
Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
research Prolactin: A Novel Neuroendocrine Regulator of Human Keratin Expression In Situ
Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
research Treatment of Vitiligo With the 308-nm Xenon Chloride Excimer Laser
The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
research Laser Treatment for Female Facial Hirsutism: Are Quality-of-Life Benefits Sustainable?
Laser hair removal improves quality of life but emotional benefits decrease over time, suggesting more treatments are needed for lasting effects.
research Feline Atopic Dermatitis: A Retrospective Study of 45 Cases (2001–2012)
Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Review of Quality of Life Studies in Women with Alopecia
Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.
research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Clinical, Ultrasound, and Hormonal Markers of Androgenicity in Acne Vulgaris
Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.
research Murine Skin as a Target for Melatonin Bioregulation
Melatonin affects mouse skin and may regulate skin functions.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study
The most common hair loss type at specialist clinics is androgenetic alopecia, especially in younger men, followed by alopecia areata and telogen effluvium, with differences seen across regions.
research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research Keratinocytes Regulate the Function of Melanocytes
Keratinocytes control how melanocytes work.
research Cutaneous Effects of the Most Commonly Used Antidepressant Medication, the Selective Serotonin Reuptake Inhibitors
Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.
research Drugs and Hair Loss: Mechanisms and Clinical Implications
Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.
research Experimental Protein-Energy Malnutrition in Baby Baboons
Malnutrition severely harms growth and development in young baboons.