research A 30-Year Follow-Up of Wax Injection for the Prevention of Androgenic Alopecia
Wax injection did not stop hair loss and caused changes to the skull.
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research Finasteride
Finasteride caused serious side effects and led to six suicides.
research Finasteride: Suicidality or Psychological Adverse Events
Finasteride use linked to increased suicidality in patients under 45.
research No Increased Risk of Cardiovascular Events with Dutasteride vs Finasteride
Dutasteride and finasteride have equal safety for treating BPH without increased heart risk.
research Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy
Methylation in specific gene region causes finasteride resistance in some BPH patients.
research Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria
PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
research Mechanisms and Applications of the Anti-Inflammatory Effects of Photobiomodulation
Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research ACOG Practice Bulletin No. 108: Polycystic Ovary Syndrome
The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.
research Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair
β-catenin in the dermal papilla is crucial for normal hair growth and repair.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Mucocutaneous Reactions to Chemotherapy
Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin
Noggin is necessary to start the hair growth phase in skin after birth.
research Dermatoses of Pregnancy
Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
research Gender-Linked Differences in Human Skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways
Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
research Hair Cosmetics: An Overview
Dermatologists need to understand hair products to treat hair and scalp issues better.
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
research Guidelines for the Management of Alopecia Areata
The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.
research The Effects of Estrogens on Linear Bone Growth
Oestrogens are key for bone growth during puberty in both boys and girls.
research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration
Wnt ligands are crucial for hair growth and repair.
research Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia
Hair loss causes stress and affects mental health; treatment and support needed.
research An Update on Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
research Bioprinting of Skin Constructs for Wound Healing
Bioprinting could improve wound healing but needs more development to match real skin.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle
Minoxidil boosts hair growth by increasing cell production and survival.
research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.