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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Local anesthesia is effective, safe, and cost-saving for plastic surgery.

Feeling younger can improve health and extend life.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Chronotherapy is more effective than traditional treatment for alopecia areata.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Finasteride improves prostate cancer detection in PSA test.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

A patient with zinc depletion improved after zinc supplementation during parenteral nutrition.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

A new method using a Foley catheter on a ureteroscope makes difficult urethral catheterization easier and more effective.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

Advertising in China shifted towards entertainment, favored local brands, and played a significant role in the country's move to a consumer economy.

Pregnancy can cause symptoms similar to rheumatic diseases, making diagnosis difficult, and affects various body systems, requiring careful distinction between normal changes and serious conditions.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Histone modification is key in treating chronic inflammatory skin diseases.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

The 25Up study collected extensive data on mental disorders and related factors in Australian twins and siblings to investigate the genetics of psychiatric illnesses.