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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Plant-based products can improve hair and skin health without harmful side effects.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Adding a second method to PROTACs could improve cancer treatment.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.

Botryococcus terribilis and its compounds may promote hair growth and improve hair health.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Enzymes called PADIs play a key role in hair growth and loss.

Cinnamon can help manage symptoms of polycystic ovary syndrome, improve menstrual cycles and fertility, and positively affect cholesterol and blood sugar levels, but more research is needed to confirm these effects and find the best dosage.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.