research A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation
A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
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research Chemical and Green Synthesis of Nanoparticles and Their Efficacy on Cancer Cells
Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.
research Effect of Minoxidil on Rabbit Lens Epithelial Cell Behavior In Vitro and In Situ
Minoxidil may help prevent capsular opacification after cataract surgery.
research Meta-Analysis of Randomized Clinical Trials of Finasteride
Finasteride effectively treats BPH and hair loss but may cause sexual side effects.
research Novel PAX9 Mutation Associated with Syndromic Tooth Agenesis
A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.
research Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research Social Perceptions of Male Pattern Baldness: A Review
The review concluded that male pattern baldness is mostly seen negatively, affecting attractiveness and social appeal.
research Hair Loss and Lithium
Lithium therapy may cause temporary hair loss, with possible regrowth if treatment is stopped or continued.
research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis
Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
research Co-Secretion of Testosterone and Cortisol by a Functional Adrenocortical Oncocytoma
A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
research Pustular Allergic Contact Dermatitis from Topical Minoxidil 5%
A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.
research Stereocontrolled Synthesis of All Eight Stereoisomers of the Putative Anti-Androgen Cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Volume Rejuvenation of the Facial Upper Third
The article compares different products for rejuvenating the upper part of the face.
research Lipid Levels in Women with Androgenetic Alopecia
Women with AGA have higher lipid levels, increasing heart disease risk.
research Inhibition of Steroid 5 Alpha-Reductase with Finasteride: Sleep-Related Erections, Potency, and Libido in Healthy Men
Finasteride doesn't affect erections much, but may decrease libido in men.
research Role of Liposomal Drug-Delivery System in Cosmetics
Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
research Alopecia Areata: Immune Function and Treatment Options
The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research Urinary Steroids in Men with Male-Pattern Alopecia
Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
research Frontal Fibrosing Alopecia and Lichen Planopilaris in HLA-Identical Mother and Daughter
A mother and daughter with similar hair loss conditions and identical HLA types suggest a genetic link between the conditions.
research Efficacy of Tip Cryotherapy in the Treatment of Idiopathic Guttate Hypomelanosis: A Randomized, Controlled, Evaluator-Blinded Study
Tip cryotherapy effectively treats idiopathic guttate hypomelanosis with minimal side effects.
research Transcriptome Sequencing and Identification of Cytochrome P450 Monooxygenases Involved in the Biosynthesis of Maslinic Acid and Corosolic Acid in Avicennia Marina
Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.
research Bisphenol-A Antagonizes the Rapidly Modulating Effect of Dihydrotestosterone on Spinogenesis and Long-Term Potentiation of Hippocampal Neurons
Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
Low ERCC3 gene activity is linked to non-pigmented hair growth.
research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.
research Current Concepts in the Pathogenesis and Treatment of Acne
Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Never Too Old to Regenerate? Wound-Induced Hair Follicle Neogenesis After Secondary Intention Healing in a Geriatric Patient
An 80-year-old patient grew new hair on a wound, showing that elderly people can still regenerate hair.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Syndrome (APECED) Due to AIRE T16M Mutation in a Consanguineous Greek Girl
An 11-year-old Greek girl was diagnosed with a rare genetic disorder, highlighting the importance of genetic testing and family history.