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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Apoptosis is essential for human skin development and forming a functional epidermis.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Using the eye pressure medication latanoprost can cause excessive hair growth and darker eyelashes on the treated eye.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.