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The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Quercetin may help with PCOS symptoms, but more research is needed.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Some alternative treatments for hair loss might work, but more research is needed.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.