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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

10% minoxidil solution better promotes hair growth and reduces hair loss without significant side effects.

Finasteride 2.5 mg/day can effectively treat female hair loss.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

A complex of 5-aminolevulinic acid and glycyl-histidyl-lysine peptide may help increase hair count in male pattern hair loss without side effects.

Dutasteride may help shrink prostate cancer tumors.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Injections with 0.5% minoxidil effectively treat female hair loss, increasing hair density and thickness.

Women with skin conditions who have body image concerns often experience mental health issues and a lower quality of life.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Minoxidil 5% solution significantly improved hair density in a girl with loose anagen hair syndrome over 28 months, with no side effects.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.