research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
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research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research Feasibility of Repairing Skin Defects by VEGF165 Gene-Modified iPS-HFSCs Seeded on a 3D Printed Scaffold Containing Astragalus Polysaccharide
The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.
research Current Landscape and Emerging Therapies in Hair Loss Treatment for Androgenetic Alopecia
A new topical treatment using SAMiRNA technology shows promise in increasing hair growth for androgenetic alopecia.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going
Innovative methods are reducing animal testing and improving biomedical research.
research Nutritional Factors and Hair Loss
Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
research Modulation of Glucocorticoid Action and the Treatment of Type-2 Diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research The Pathophysiology of Polycystic Ovary Syndrome: Understanding PCOS and Its Endocrinology
The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research Syndromes of Severe Insulin Resistance
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia
New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
research Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications
Adrenal disorders can cause lasting brain and behavior issues in children.
research Telogen Effluvium: Is There a Need for a New Classification
The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
research A Comparison of Transcriptomic Patterns Measured in the Skin of Chinese Fine and Coarse Wool Sheep Breeds
Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Updates from the British Association of Dermatologists 91st Annual Meeting, 5-7 July 2011, London, UK
New treatments and management strategies for skin conditions like melanoma and Spitz naevi were discussed at the dermatologists' meeting.
research Hormones and Absence Epilepsy
Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
research The Role of the Microbiome in Scalp Hair Follicle Biology and Disease
The scalp's microorganisms significantly affect hair health and disease.
research Synaptic-Like Vesicles and Candidate Transduction Channels in Mechanosensory Terminals
SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
research 5 Alpha-Reductase Inhibitory Potential of Solanum Nigrum for Alopecia Management
Solanum nigrum may help treat hair loss.
research Highlighting Nuances of Blue Light Phototherapy: Mechanisms and Safety Considerations
Blue light therapy is safe for skin and may protect against UV radiation.
research The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration
WNT signaling is crucial for skin development and healing.
research Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending
The research identified key proteins and genes that may influence wool bending in goats.
research Contemporary Medical Therapy for Polycystic Ovary Syndrome
New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.