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Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Fat cells in the skin help start healing and form important repair cells after injury.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Minoxidil helped bald patient regrow hair.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.