19 citations,
July 2006 in “Physiology & Behavior” Finasteride slows down motherly behavior in first-time pregnant rats.
18 citations,
September 2015 in “Clinical Endocrinology” Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.
15 citations,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
15 citations,
November 2015 in “Pharmacopsychiatry” α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.
13 citations,
March 2019 in “Journal of Dermatological Treatment” Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
13 citations,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
12 citations,
August 2018 in “Psychiatry research” Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
12 citations,
January 2013 in “Alcohol and Alcoholism” Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
11 citations,
August 2014 in “Current Urology Reports” Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
10 citations,
February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
9 citations,
January 2018 in “American Journal of Men's Health” Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
7 citations,
January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
7 citations,
October 2017 in “Behavioural Pharmacology” Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
5 citations,
November 2020 in “JAMA Dermatology” Finasteride may cause side effects; more research needed.
4 citations,
July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
4 citations,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
3 citations,
August 2020 in “Urology Journal” Using 5-alpha reductase inhibitors may increase the risk of mild depression.
2 citations,
May 2021 in “Molecules” A new method was created to analyze certain chemicals in the urine of alopecia areata patients, revealing they have higher metanephrine content. This method can also be used for other related diseases.
2 citations,
January 2010 in “Hormone Molecular Biology and Clinical Investigation” Low dose finasteride decreases certain steroids, possibly increasing depression risk.
May 2024 in “Brazilian Journal of Hair Health” Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.
April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
May 2006 in “Frontiers in Neuroendocrinology” Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.
October 2004 in “European Neuropsychopharmacology” Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.
June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
February 2020 in “Bulletin of Experimental Biology and Medicine” Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.
April 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” January 2016 in “Medicinski Podmladak” 35 citations,
November 2019 in “Frontiers in Neuroendocrinology” Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.