96 citations,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
5 citations,
October 2016 in “Experimental Dermatology” Activin A is important for creating new hair follicles.
1 citations,
March 2022 in “Journal of Dermatological Science” Adding TERT and BMI1 to certain skin cells can improve their ability to create hair follicles in mice.
May 2024 in “Journal of Advanced Research” Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
11 citations,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” Resveratrol may help hair grow, but more research is needed.
January 2021 in “Figshare” Metformin helps regenerate hair follicles in lab conditions.
Some fibroblast growth factors may promote hair growth similarly to minoxidil and could potentially treat hair loss.
291 citations,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.
April 2023 in “Journal of Investigative Dermatology” cp-asiAR may effectively treat hair loss by targeting androgen receptors.
November 2022 in “Molecular Pharmaceutics” cp-asiAR may effectively treat androgenetic alopecia by promoting hair growth and reducing androgen receptor activity.
The conclusion is that a treatment called cp-asiAR can reduce hair loss and promote hair growth, making it a potential new therapy for androgenetic alopecia.
27 citations,
November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
30 citations,
September 2004 in “Experimental Dermatology” Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.
7 citations,
January 2016 in “Methods in molecular biology” Mouse hair follicle stem cells were successfully isolated and used to regenerate hair follicles with two different methods.
24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
56 citations,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
January 2012 in “Methods in pharmacology and toxicology” Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
79 citations,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
40 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
23 citations,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
January 2024 in “PloS one” Rat hair-follicle stem cells can become heart cells with specific supplements.
6 citations,
August 2015 in “Acta histochemica” Lysozyme might help mouse hair grow.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.
31 citations,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
16 citations,
April 2021 in “International Journal of Molecular Sciences” Micro-current stimulation may promote hair growth more effectively than standard treatments.
42 citations,
February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.