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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Allopregnanolone changes gene expression in glioblastoma cells.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

HIF-1α is important for hair growth and could be a treatment target for hair loss.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

GPR40 agonists help hair growth through the protein ANGPTL4.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.

Activating Notch signaling can kill basal cell carcinoma cells.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.

Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.

Loss of Msx2 function causes eye development issues similar to Peters anomaly.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Activin A promotes ear hair cell development, while follistatin delays it.