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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Androgenetic alopecia in women needs more research and better management strategies.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.