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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Five Weimaraners had a milder form of color dilution alopecia causing hair loss and skin issues.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Some masked palm civets in Japan have a skin disease caused by mites.

A woman's liver problems improved after she stopped taking spironolactone.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Hormones and genes affect hair growth and male baldness.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

Cantú syndrome may be linked to pituitary adenomas.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Heat damages hair, with Asian hair losing more protein than Caucasian hair.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Different tests are used to see how hair care products affect hair, and choosing the right test is important for accurate results.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Wheat straw is valuable for its health benefits and various industrial uses.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.