research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
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research Nutritional and Potential Health Effects of Pumpkin Seeds
Pumpkin seeds are nutritious and can improve health, making them useful for cheaper, sustainable food.
research Efficient Scarless Skin Regeneration Enabled by Loading Micronized Amnion in a Bioinspired Adhesive Wound Dressing
A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
research Extraction of Keratin from Human Hair Waste for Copolymerization with Nitrile Butadiene Rubber
Human hair keratin mixed with rubber slightly improves its strength and biodegradability.
research Epidermal Stem Cells Do Not Communicate Through Gap Junctions
Epidermal stem cells don't use gap junctions to communicate.
research Defining the Cellular Environment in the Organ of Corti Following Extensive Hair Cell Loss: A Basis for Future Sensory Cell Replacement in the Cochlea
The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
Special cell particles from macrophages can help hair grow.
research Identification of Sirtuin 1 as a Promising Therapeutic Target for Hypertrophic Scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research A Counter Gradient of Activin A and Follistatin Instructs the Timing of Hair Cell Differentiation in the Murine Cochlea
Activin A and follistatin control when hair cells develop in mouse ears.
research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway
Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells
Exosomes from human fat stem cells can potentially enhance hair growth and survival, providing a new possible treatment for hair loss.
research LncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via Trans-Regulatory Actions
lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.
research Klhl24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia
A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.
research Limonin, a Component of Immature Citrus Fruits, Activates Anagen Signaling in Dermal Papilla Cells
Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.
research Connarus Semidecandrus Jack Exerts Anti-Alopecia Effects by Targeting 5α-Reductase Activity and an Intrinsic Apoptotic Pathway
Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Anti-Aging Potential of Platelet Rich Plasma: Evidence from Osteoarthritis and Applications in Senescence and Inflammaging
PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.
research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner
Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.
research Antiandrogenic Activity of Riboflavin 5′-Phosphate (FMN) in 22Rv1 and LNCaP Human Prostate Cancer Cell Lines
Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
research Bullous Pyoderma Gangrenosum Occurring on a Cesarean Section Scar
Bullous pyoderma gangrenosum can develop on cesarean scars and may require steroids for treatment.
research The Metabolites of Bifidobacterium Longum BB536 Alleviate DHT-Damaged Human Dermal Papilla Cells by Activating WNT/β-Catenin Signaling
Bifidobacterium longum BB536 metabolites may help treat hair loss by repairing and promoting hair cell growth.
research Network Pharmacology Reveals Curcuma Aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia
Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.
research Bioinspired Engineering of ADSC Nanovesicles in Thermosensitive Hydrogel to Enhance Autophagy of Dermal Papilla Cells for Androgenetic Alopecia Treatment
New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.
research MTurq2-Col4a1 Mouse Model Allows for Live Visualization of Mammalian Basement Membrane Development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research New Target for Minoxidil in the Treatment of Androgenetic Alopecia
Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
research Cold Atmospheric Microwave Plasma Stimulates Dermal Papilla Cell Proliferation by Inducing Beta-Catenin Signaling
Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.
research Androgenetic Alopecia as a Complication of SARS-CoV-2 Infection
People with androgenetic alopecia may have a higher risk of severe COVID-19.