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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

KGF and activin are crucial for skin healing and repair.

SHBG may be a useful early indicator and treatment target for PCOS.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Herbal remedies can cause adverse effects and need more safety research.

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Excess androgens may cause PCOS, not just be a symptom.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

PRP and PRF show promise for hair growth but need more research for consistent and safe use.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.