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The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Herbal remedies can cause adverse effects and need more safety research.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Targeting colon cancer stem cells might lead to better treatment results.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Auxin and ethylene hormones both work together and against each other to control plant growth.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.