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Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

The Gsdma3 gene is essential for normal hair development in mice.

Astressin-B can reverse and prevent hair loss in stressed mice.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.

Hair changes can indicate systemic diseases or medication effects.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.

Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Schizophrenia risk genes may affect early brain development, contributing to the disease.

Different types of hair loss require specific treatments, and new treatments are being developed.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

A boy's skin fragility and sparse hair were caused by a genetic mutation affecting skin cell adhesion.

Fasting in hens affects thyroid hormones, which regulate feather and hair growth.

The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.