19 citations,
January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
3 citations,
March 2021 in “Metabolites” Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
January 2018 in “Springer eBooks” Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
27 citations,
July 1990 in “International Journal of Dermatology” A pulsed electrical field safely and effectively increased hair growth.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
5 citations,
July 2000 in “Southern Medical Journal” Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.
4 citations,
August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
54 citations,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
49 citations,
July 2009 in “Fitoterapia” Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
32 citations,
January 2000 in “Skin pharmacology and physiology” Certain substances that block a specific protein help promote hair growth.
November 2018 in “Springer eBooks” Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
19 citations,
December 2018 in “Experimental and Molecular Medicine” Small molecule IM boosts hair growth by changing stem cell metabolism.
10 citations,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
9 citations,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
6 citations,
February 2018 in “PLOS ONE” Insect wax, especially its policosanol content, may help hair regrow by changing hair follicle phases and increasing nutrient supply.
3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
3 citations,
November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
1 citations,
May 2017 in “InTech eBooks” Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
1 citations,
August 2002 in “Zeitschrift für Hautkrankheiten” Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
August 2024 in “Frontiers in Pharmacology” Antibody treatments show promise for hair loss but need more research.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
23 citations,
December 2004 in “Differentiation” Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
10 citations,
August 2020 in “Journal of Bioscience and Bioengineering” Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.
12 citations,
September 2014 in “Journal of Food Science and Nutrition” Platycarya strobilacea extract is a strong antioxidant that can grow hair better than minoxidil.
1 citations,
December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
June 2024 in “Acta dermato-venereologica” Topical minoxidil effectively stimulates hair growth in men with hair loss.