research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
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research Acquired Trichomegaly of the Eyelashes and Hypertrichosis Induced by Bimatoprost
Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Androgen Receptor: A Promising Therapeutic Target in Breast Cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Chemical and Green Synthesis of Nanoparticles and Their Efficacy on Cancer Cells
Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.
research Disease Versus Disease: How One Disease May Ameliorate Another
Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
research Risk-Benefit Ratio in the Treatment of Psoriasis with Systemic Retinoids
Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia
Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
research Cutaneous Wound Healing: Canine Allogeneic ASC Therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli
Finasteride reduces response to stress and rewards, affecting behavior and mental health.
research Evaluation of Acute, Subacute Oral Toxicity and Wound Healing Activity of Mother Plant and Callus of Teucrium Polium L. Subsp. Geyrii Maire from Algeria
Teucrium polium extracts are non-toxic and effectively speed up wound healing.
research Honokiol Protects Skin Cells Against Inflammation, Collagenolysis, Apoptosis, and Senescence Caused by Cigarette Smoke Damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
research Permeation of Topically Applied Magnesium Ions Through Human Skin Is Facilitated by Hair Follicles
Hair follicles help magnesium get through the skin more effectively.
research Green Tea in Dermatology: Myths and Facts
Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.
research Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice
MED1 affects skin wound healing differently in young and old mice.
research Eosinophilic Fasciitis Associated With Tryptophan Ingestion
High doses of tryptophan may cause eosinophilic fasciitis.
research The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites
Juniperus plants contain compounds with potential for developing various medical treatments.
research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism
Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
research Atrichia With Papular Lesions Resulting From a Novel Insertion Mutation in the Human Hairless Gene
Researchers found a new mutation causing total hair loss from birth.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Lactoferrin Promotes Hair Growth in Mice and Increases Dermal Papilla Cell Proliferation Through Erk/Akt and Wnt Signaling Pathways
Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
research Curcuma Aeruginosa Roxb. Essential Oil Slows Hair Growth and Lightens Skin in Axillae: A Randomized, Double-Blinded Trial
Curcuma aeruginosa essential oil effectively reduces hair growth and lightens underarm skin.
research Structures of Three Polycystic Kidney Disease-Like Domains from Clostridium Histolyticum Collagenases ColG and ColH
The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Cutaneous Xanthomas With Concurrent Demodicosis and Dermatophytosis in a Cat
A cat with skin bumps and itching had high blood fats and skin infections, which improved with diet and medication changes.
research Dermatologic Diseases and Problems of Women Throughout the Life Cycle
Women experience various skin issues at different life stages, requiring careful treatment and awareness.
research High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease
Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.