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Stem cell niches support, regulate, and coordinate stem cell functions.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

TSH is usually the only test needed to check thyroid function in primary care.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Very few people experience increased hair growth after laser hair removal, especially those with darker skin and black hair.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.