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Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

New technologies help us better understand how skin microbes affect skin diseases.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Correct testosterone levels for age to treat prostate cancer, using low dose treatments as necessary.

Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Fat cells in the skin help start healing and form important repair cells after injury.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

New treatments for male hypogonadism are effective and should be personalized.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.