Natural products may help treat hair loss by promoting hair growth with fewer side effects.
2 citations,
December 2022 in “Pharmaceutics” The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
36 citations,
August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
5 citations,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
7 citations,
January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
November 2024 in “The Journal of Cell Biology” Basement membrane changes are crucial for hair follicle development.
3 citations,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
63 citations,
November 2012 in “Journal of Cellular Biochemistry” Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
15 citations,
July 2020 in “Stem Cell Research & Therapy” Stem cell therapy helps heal burn wounds, especially second-degree burns, by promoting blood vessel growth and reducing inflammation.
6 citations,
January 2021 in “Annals of Dermatology” 650 nm red light helps hair grow and prevents hair loss by affecting certain genes and biological processes.
1 citations,
December 2016 in “Trichology and cosmetology:” Panax ginseng might help with hair growth and has fewer side effects than synthetic treatments.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
8 citations,
September 2021 in “EMBO Molecular Medicine” A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.
14 citations,
January 2016 in “Biochemical and Biophysical Research Communications” Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.
15 citations,
August 2020 in “American Journal of Pathology” Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
38 citations,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Blue light can help hair grow by affecting certain receptors in hair follicles.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
14 citations,
September 2018 in “International Journal of Molecular Sciences” Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.
8 citations,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
5 citations,
January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
137 citations,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
6 citations,
September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
38 citations,
September 2017 in “Oncologist” Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
135 citations,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.