67 citations,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
54 citations,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
53 citations,
September 2014 in “Reproductive Biology and Endocrinology” Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
33 citations,
August 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
29 citations,
January 2009 in “Gynecological Endocrinology” Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.
26 citations,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
21 citations,
February 2016 in “Reproductive Biomedicine Online” The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
20 citations,
April 2017 in “Journal of the American Academy of Dermatology” Antimalarial drugs, especially chloroquine, can effectively treat granuloma annulare.
17 citations,
December 2011 in “Journal of the European Academy of Dermatology and Venereology” People with vitiligo may have a lower risk of heart disease.
16 citations,
February 2016 in “Gynecological Endocrinology” Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
16 citations,
November 1998 in “Fertility and sterility” Doctors used to view PCOS too narrowly, but now understand that insulin resistance is a key factor in the condition.
14 citations,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
11 citations,
April 2018 in “Nutrition Research” Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.
10 citations,
March 2016 in “The Journal of Obstetrics and Gynecology of India” The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.
8 citations,
December 2016 in “Revista Medica De Chile” Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
8 citations,
November 2012 in “Journal of Endocrinological Investigation” Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.
7 citations,
January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
7 citations,
December 2020 in “Endocrine-related Cancer” The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.
7 citations,
October 2006 in “Medical hypotheses” UV light might cause excessive hair growth by increasing PGE2 in the skin.
6 citations,
August 2022 in “International Journal of Molecular Sciences” EDA signaling is linked to skin disorders, various cancers, and liver disease.
6 citations,
May 2020 in “Scientific reports” Researchers identified genes and proteins that may influence wool thickness in sheep.
5 citations,
June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
5 citations,
November 2012 in “The Journal of Urology” Early hair loss may indicate future prostate issues.
4 citations,
February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
3 citations,
June 2004 in “Reviews in gynaecological practice” Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.
2 citations,
August 2022 in “Middle East Fertility Society Journal” The new rodent model successfully mimics non-lean human PCOS symptoms.
2 citations,
March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
1 citations,
February 2024 in “Diversity” African plants can treat hair issues and may help with diabetes.
1 citations,
January 2021 in “Prague medical report” Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.
October 2023 in “Benha Journal of Applied Sciences” Insulin resistance may contribute to hair loss in people with androgenic alopecia.