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Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Nerves are crucial for the regeneration of various body parts in many animals.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Sebocytes play a key role in controlling androgen levels in human skin.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.