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Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Wnt ligands are crucial for hair growth and repair.

Keratinocytes control how melanocytes work.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The skin and thymus develop similarly to protect and support immunity.

Putting α-methylspermidine on mouse skin can start hair growth.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Horizontal scalp biopsy sections are better for diagnosing alopecia areata, showing fewer hair follicles and more miniaturized hairs.

Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.

Hair loss due to scarring can be treated by reducing inflammation, removing scar tissue, and transplanting hair. The Follicular Unit Extraction technique is effective but requires skill and time. Future focus should be on scar-less healing methods.

The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.

Human stem cells can help form hair follicles in mice.