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Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Etretinate has only moderate effects on localized scleroderma and lichen sclerosus.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

About 3% of high school girls aged 14-18 in Isfahan, Iran, have polycystic ovary syndrome.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.