research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
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960-990 / 1000+ results research Novel Insights Into Ascorbic Acid Skin Permeation
The best way to apply vitamin C to the skin is with a nanostructured lipid carrier formulation.
research Micro-Regional Transcriptome Reveals Local Dermal-Epidermal Intercorrelation in Atopic Dermatitis
Atopic dermatitis shows a link between skin layers in inflammation, detectable with detailed gene analysis.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Hair Follicle Stem Cell Progeny Heal Blisters While Pausing Skin Development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
research Upregulation of SERPINB3/B4 and S100A7-9 in Hidradenitis Suppurativa/Acne Inversa
Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.
research Humanized Mouse Model for Hair Follicle Studies
Researchers successfully used nude mice to study human hair growth, which could help with future hair research.
research Case Number 19 of Perforating Necrobiosis Lipoidica Worldwide
The document reports the first case of a rare skin condition in Colombia, the 19th case worldwide.
research Anterolateral Leg Alopecia: Unknown Entity or Underreported?
Anterolateral leg alopecia is a benign, nonprogressive hair loss condition on the lower legs that is not well understood and may resolve on its own.
research Hair And Nail Disorders: Trichoscopic Features Of The Normal Dark Scalp
Hair and nail disorders can cause changes in scalp pigmentation, especially with sun exposure and alopecia.
research Centrosomes Are Required for the Normal Development of the Skin Epithelium
Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
research Stimulation of Hair Follicle Stem Cell Proliferation Through an IL-1α Dependent Activation of γδ T-Cells
Certain immune cells, when activated by specific signals, can encourage hair growth.
research HIF1A Stabilization in the Human Hair Follicle Promotes Glycolysis
Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
research Glutathione Distribution by Quantitative MALDI Imaging in Reconstructed Human Skin Upon Activation of GSH Biosynthesis by Nrf2 Pathway Activator
Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
research Alternative Splicing Factor Esrp1 Controls Homeostasis of Skin by Regulating Barrier Formation and Function
Esrp1 is important for skin health by helping form and maintain the skin barrier.
research Toxicological Responses in Keratinocyte Interfollicular Stem Cells
Toxins can disrupt skin stem cell balance, causing skin overgrowth or ulceration.
research Surgical Treatments of Leukodermas Other Than Vitiligo Vulgaris
Hair transplantation showed the most promise for repigmenting white hair, especially for eyebrows and eyelashes.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
research Investigation Into the Role of HIF-1A Stabilization in Hair Follicle Metabolism
Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
research Homeostatic Activation of Epidermal HSD11b1 Affects Skin Innervation and Non-Histaminergic Itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research Comparison of Comedolytic Effect of Benzoyl Peroxide and Adapalene in Rhino Mice
Benzoyl peroxide and adapalene gels work differently to reduce acne in mice.
research Advances in Aesthetic Therapies: Platelet-Rich Plasma Procedure for the Treatment of Alopecia
Platelet-rich plasma (PRP) is an effective treatment for hair loss that involves scalp injections and requires ongoing maintenance.
research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research The Abnormal Skin Structure of Newborn Wistar Rats Maternally Treated with Aspartame: Histological and Immunohistochemical Study
Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.
research Polycomb-Mediated Repression and Sonic Hedgehog Signaling Regulate Merkel Cell Specification
Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.
research Chromatin Remodeler Lymphoid-Specific Helicase (Lsh) Is a Critical Determinant Controlling Postnatal Epidermal Growth, Differentiation, and Response to Injury
Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research The Skin at Different Ages
Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.
research In This Issue
Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.