research Fate Tracing of DNA-Damaged Hair Follicle Stem Cells and Their Seno-Differentiation Clearance Out of the Niche
Damaged hair follicle stem cells may leave the skin to help maintain youthfulness.
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research A Non-Cell Autonomous Dermal Hedgehog Signaling Mechanism for Follicular Neoplasia and Induction
Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
research Cryo-EM and Molecular Dynamics of TRPV3 Channel in Activated State Reveal Structural Features Implicated in Severe Itch and Hyperkeratosis
The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
research Data from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Ribonucleotide excision repair is crucial to prevent skin cancer.
research Data from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Ribonucleotide excision repair is crucial to prevent skin cancer.
research Comparative Histopathological Analyses of Non-Scarring Alopecia in Systemic Lupus Erythematosus Patients in Lagos, Nigeria
The main difference in hair loss for lupus patients is smaller and fewer sebaceous glands.
research Proliferative Necrotizing Otitis Externa in Two Young Cats
Two young cats with a severe ear and skin condition improved with immune system-targeting treatments.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Varicella-Zoster Virus in Actively Spreading Segmental Vitiligo Skin
The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.
research Mechanisms of Cutaneous Adverse Events During Targeted Cancer Therapy
Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.
research Induction Of Tissue-Specific Premature Stem Cell Aging Promotes Senescence-Like Phenotypes In Remote Multiple Organs
Aging in one type of stem cell can cause aging-like changes in various organs.
research Dissecting the Role of the Common Neurotrophin Receptor CD271 in the Skin: Generation and Characterization of a Novel Mouse Model with Keratinocyte-Specific Conditional Deletion
Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
research Induction of Type 17 Collagen Decreases Ultraviolet B-Induced Cellular Senescence in Human hTert/KER-CT Keratinocytes
Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.
research Physiological Function of Krox20 (Egr2) in Epithelial Stem Cells
Krox20 is important for maintaining stem cells in the skin and affects hair growth and color.
research The Early Region of Trichodysplasia Spinulosa Polyomavirus Drives Proliferation, Altered Differentiation, and Ectopic Expression of Hair Follicle Differentiation Markers in Interfollicular Tail Epidermis
The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis And Promotes Regeneration In Spiny Mice (Acomys)
A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research Desmoglein 3-Mediated Mechanical Transadhesion Controls Epithelial Stem Cell Quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Histopathological Study of Epithelial, Melanocytic and Adnexal Tumors of Skin: A Retrospective Study in a Tertiary Care Centre
Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.
research Major Approaches of Molecular and Physiopathological Mechanisms for Hormonal Treatment of Melasma: A Systematic Review
Estrogens and progesterone are key in regulating melasma pigmentation.
research In Focus In HCB: The Role Of Cholesterol Transporter Proteins In The Human Hair Cycle, The Epithelial-To-Mesenchymal Transition And Primary Cilia In Urothelial Cancers, The Impact Of Ovarian Hormones And Choriogonadotropin On Endometrial Cell Polarity Before Implantation, And The Effects Of Epidermal Maturation And UV-Irradiation On The Protein rCLCA2 In Rodent Keratinocytes And Skin
The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.
research Transcriptomic Analysis to Identify Protective Dermal Papilla Signature in Occipital Scalp
The research found genes that may protect certain scalp cells from hair loss.
research Bacteria Induce Skin Regeneration via IL-1β Signaling
Bacteria can help skin regenerate through a process called IL-1β signaling.
research Hair Cycle Regulation by a Mitochondrially Localized Protein: Is MPZL3 a Central Component of the Elusive Hair Cycle Clock?
MPZL3 protein is important for controlling hair growth cycles.
research Chromatin Architectural Protein CTCF Regulates Terminal Keratinocyte Differentiation in the Developing Epidermis and Hair Follicles
CTCF protein is essential for skin and hair follicle development in mice.
research Faculty Opinions Recommendation of GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on specific stem cells.
research Role of PRP (Platelet-Rich Plasma) in Alopecia Areata: A Literature Review
PRP may help hair growth in alopecia areata without major side effects, but more research is needed.
research Study on the Effectiveness of Zinc Pyrithione in Anti-Dandruff Shampoo Formulations
Zinc pyrithione in shampoo effectively treats dandruff.
research Molecular and Pathological Studies on Sarcoptes Scabiei in Sheep in Ismailia Province, Egypt
10.5% of sheep in Ismailia, Egypt, had Sarcoptes scabiei, causing skin issues.