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The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

KGF and activin are crucial for skin healing and repair.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Activating TRPV3 stops human hair growth.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Fullerenes show potential in skin care but need more safety research.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Prolactin affects hair growth cycles and can cause early hair follicle regression.