research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
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research Smoking and the Skin: Effects and Therapeutic Potential
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Visually Scoring Hirsutism
The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation
Desmoglein 4 is controlled by specific proteins that affect hair growth.
research Werner's Syndrome: Incidental Finding During Pregnancy
A pregnant woman with Werner's syndrome died during childbirth, but her baby survived and did not have the syndrome.
research Adult Onset Still Disease: A Case Study
High-dose corticosteroid treatment helped improve symptoms in a patient with Adult Onset Still Disease.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Influence of Substance P on Cultured Sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research The Spectrum of Nephrocutaneous Diseases and Associations
Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
research British Society for Pediatric Dermatology Annual Meeting, Sheffield, 18-19 November 2016
The meeting highlighted the importance of genetic testing and multidisciplinary approaches in pediatric dermatology.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Peroxisome Proliferator Activated Receptors Gamma Serum Levels and Gene Polymorphism in Frontal Fibrosing Alopecia: A Case-Control Study
Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
research Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss
A gene variant increases the risk of a type of hair loss by affecting hair protein production.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Ultraviolet B Irradiation Increases the Expression of Inflammatory Cytokines in Cultured Sebocytes
UV-B light increases inflammation-related substances in acne-related skin cells.
research Fluridil, a Rationally Designed Topical Agent for Androgenetic Alopecia
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Transgenic HPV11-E2 Protein Modulates URR Activity In Vivo
The E2 protein affects gene activity in hair follicles of mice.
research How Different Is Human Hair? A Critical Appraisal of Global Hair Fibre Characteristics and Properties Towards Defining a More Relevant Framework for Hair Type Classification
Human hair varies widely and should be classified by curl type rather than race.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways
There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.