Search

everythinglearnresearchcommunity

for

Search:↓

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.

A woman with severe angioedema improved significantly after treatment with rituximab.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Anabolic steroid users may face higher risk of severe COVID-19.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Four-amino acid part makes enzyme sensitive to finasteride.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.