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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Vitamin D receptor is crucial for starting hair growth after birth.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Thyroid function affects skin health, with a complex interaction between the two.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Hair follicle regeneration possible, more research needed.

Autophagy is important for human hair growth and health.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Some alternative treatments for hair loss might work, but more research is needed.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.