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Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Current research explores hair growth drugs, while future research aims for personalized treatments.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Androgens may block hair growth signals, targeting this could treat hair loss.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.

AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

New treatments for hair loss may target specific pathways and generate new hair follicles.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.